Parrella, Edoardo
Parrella, Edoardo
Facoltà Dipartimentale di Medicina
A Polyphenol-Enriched Supplement Exerts Potent Epigenetic-Protective Activity in a Cell-Based Model of Brain Ischemia
2019-01-01 Faggi, Lara; Porrini, Vanessa; Lanzillotta, Annamaria; Benarese, Marina; Mota, Mariana; Tsoukalas, Dimitris; Parrella, Edoardo; Pizzi, Marina
Acetylation state of RelA modulated by epigenetic drugs prolongs survival and induces a neuroprotective effect on ALS murine model
2018-01-01 Schiaffino, Lorenzo; Bonafede, Roberta; Scambi, Ilaria; Parrella, Edoardo; Pizzi, Marina; Mariotti, Raffaella
Age-Dependent Neuropsychiatric Symptoms in the NF-κB/c-Rel Knockout Mouse Model of Parkinson’s Disease
2022-01-01 Parrella, Edoardo; Del Gallo, Federico; Porrini, Vanessa; Gussago, Cristina; Benarese, Marina; Fabene, Paolo Francesco; Pizzi, Marina
Antitumor activity of the retinoid-related molecules (E)-3-(4⠲- hydroxy-3⠲-adamantylbiphenyl-4-yl)acrylic acid (ST1926) and 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) in F9 teratocarcinoma: Role of retinoic acid receptor γ and retinoid-independent pathways
2006-01-01 Parrella, Edoardo; Giannì, Maurizio; Fratelli, Maddalena; Barzago, Maria Monica; Raska Jr., Ivan; Diomede, Luisa; Kurosaki, Mami; Pisano, Claudio; Carminati, Paolo; Merlini, Lucio; Dallavalle, Sabrina; Tavecchio, Michele; Rochette-Egly, Cecile; Terao, Mineko; Garattini, Enrico
Beneficial and Dimorphic Response to Combined HDAC Inhibitor Valproate and AMPK/SIRT1 Pathway Activator Resveratrol in the Treatment of ALS Mice
2022-01-01 Bankole, Oluwamolakun; Scambi, Ilaria; Parrella, Edoardo; Muccilli, Matilde; Bonafede, Roberta; Turano, Ermanna; Pizzi, Marina; Mariotti, Raffaella
c-Rel deficient mice, a mouse model of “spreading” PD-like pathology
2016-01-01 Parrella, Edoardo; Bellucci, Arianna; Porrini, Vanessa; Lanzillotta, Annamaria; Benarese, Marina; Vegezzi, Gaia; Baiguera, Cristina; Antonini, Angelo; Franco Spano, Pier; Pizzi, Marina
CHF5074 (CSP-1103) induces microglia alternative activation in plaque-free Tg2576 mice and primary glial cultures exposed to beta-amyloid
2015-01-01 Porrini, Vanessa; Lanzillotta, Annamaria; Branca, Caterina; Benarese, Marina Augusta; Parrella, Edoardo; Lorenzini, L.; Calzà, L.; Flaibani, R.; Spano, Pier Franco; Imbimbo, B. P.; Pizzi, Marina
Fasting-mimicking diet cycles reduce neuroinflammation to attenuate cognitive decline in Alzheimer's models
2022-01-01 Rangan, Priya; Lobo, Fleur; Parrella, Edoardo; Rochette, Nicolas; Morselli, Marco; Stephen, Terri-Leigh; Cremonini, Anna Laura; Tagliafico, Luca; Persia, Angelica; Caffa, Irene; Monacelli, Fiammetta; Odetti, Patrizio; Bonfiglio, Tommaso; Nencioni, Alessio; Pigliautile, Martina; Boccardi, Virginia; Mecocci, Patrizia; Pike, Christian J; Cohen, Pinchas; Ladu, Mary Jo; Pellegrini, Matteo; Xia, Kyle; Tran, Katelynn; Ann, Brandon; Chowdhury, Dolly; Longo, Valter D
From preclinical stroke models to humans: Polyphenols in the prevention and treatment of stroke
2021-01-01 Parrella, Edoardo; Gussago, Cristina; Porrini, Vanessa; Benarese, Marina; Pizzi, Marina
Glial response and neuronal modulation induced by epidural electrode implant in the pilocarpine mouse model of epilepsy
2024-01-01 Spagnoli, Giulia; Parrella, Edoardo; Ghazanfar Tehrani, Sara; Mengoni, Francesca; Salari, Valentina; Nistreanu, Cristina; Scambi, Ilaria; Sbarbati, Andrea; Bertini, Giuseppe; Fabene, Paolo Francesco
Inhibition of the peptidyl-prolyl-isomerase Pin1 enhances the responses of acute myeloid leukemia cells to retinoic acid via stabilization of RARα and PML-RARα
2009-01-01 Gianni', Maurizio; Boldetti, Andrea; Guarnaccia, Valeria; Rambaldi, Alessandro; Parrella, Edoardo; Raska Jr., Ivan; Rochette-Egly, Cecile; Del Sal, Giannino; Rustighi, Alessandra; Terao, Mineko; Garattini, Enrico
Insulin/IGF-I and related signaling pathways regulate aging in nondividing cells: From yeast to the mammalian brain
2010-01-01 Parrella, Edoardo; Longo, Valter D.
Mild inflammatory profile without gliosis in the c-rel deficient mouse modeling a late-onset parkinsonism
2017-01-01 Porrini, Vanessa; Mota, Mariana; Parrella, Edoardo; Bellucci, Arianna; Benarese, Marina; Faggi, Lara; Tonin, Paolo; Spano, Pier F.; Pizzi, Marina
Neuroprotective and Anti-Apoptotic Effects of CSP-1103 in Primary Cortical Neurons Exposed to Oxygen and Glucose Deprivation
2017-01-01 Porrini, Vanessa; Sarnico, Ilenia Tiziana; Benarese, Marina Augusta; Branca, Caterina; COELHO DA MOTA, Mariana; Lanzillotta, Annamaria; Bellucci, Arianna; Parrella, Edoardo; Faggi, Lara; Spano, Pier Franco; Imbimbo, Bruno Pietro; Pizzi, Marina
Neuroprotective epi-drugs quench the inflammatory response and microglial/macrophage activation in a mouse model of permanent brain ischemia
2020-01-01 Mota, Mariana; Porrini, Vanessa; Parrella, Edoardo; Benarese, Marina; Bellucci, Arianna; Rhein, Sina; Schwaninger, Markus; Pizzi, Marina
NF-κB in Innate Neuroprotection and Age-Related Neurodegenerative Diseases
2015-01-01 Lanzillotta, Annamaria; Porrini, Vanessa; Bellucci, Arianna; Benarese, Marina Augusta; Branca, Caterina; Parrella, Edoardo; Spano, Pier Franco; Pizzi, Marina
NF-κB unbalance and dysfunction in acute and age-related neurodegenerative disease
2014-01-01 Lanzillotta, A; Porrini, V; Bellucci, A; Benarese, M; Branca, C; Parrella, E; Spano, Pf; Pizzi, M
NF-κB/c-Rel deficiency causes Parkinson's disease-like prodromal symptoms and progressive pathology in mice
2019-01-01 Parrella, Edoardo; Bellucci, Arianna; Porrini, Vanessa; Benarese, Marina; Lanzillotta, Annamaria; Faustini, Gaia; Longhena, Francesca; Abate, Giulia; Uberti, Daniela; Pizzi, Marina
Nuclear Factor-κB Dysregulation and α-Synuclein Pathology: Critical Interplay in the Pathogenesis of Parkinson’s Disease
2020-01-01 Bellucci, A.; Bubacco, L.; Longhena, F.; Parrella, Edoardo; Faustini, G.; Porrini, V.; Bono, F.; Missale, C.; Pizzi, M.
P38MAPK-dependent phosphorylation and degradation of SRC-3/AIB1 and RARα-mediated transcription
2006-01-01 Giannì, Maurizio; Parrella, Edoardo; Raska Jr., Ivan; Gaillard, Emilie; Nigro, Elisa Agnese; Gaudon, Claudine; Garattini, Enrico; Rochette-Egly, Cécile
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A Polyphenol-Enriched Supplement Exerts Potent Epigenetic-Protective Activity in a Cell-Based Model of Brain Ischemia | 1-gen-2019 | Faggi, Lara; Porrini, Vanessa; Lanzillotta, Annamaria; Benarese, Marina; Mota, Mariana; Tsoukalas, Dimitris; Parrella, Edoardo; Pizzi, Marina | |
| Acetylation state of RelA modulated by epigenetic drugs prolongs survival and induces a neuroprotective effect on ALS murine model | 1-gen-2018 | Schiaffino, Lorenzo; Bonafede, Roberta; Scambi, Ilaria; Parrella, Edoardo; Pizzi, Marina; Mariotti, Raffaella | |
| Age-Dependent Neuropsychiatric Symptoms in the NF-κB/c-Rel Knockout Mouse Model of Parkinson’s Disease | 1-gen-2022 | Parrella, Edoardo; Del Gallo, Federico; Porrini, Vanessa; Gussago, Cristina; Benarese, Marina; Fabene, Paolo Francesco; Pizzi, Marina | |
| Antitumor activity of the retinoid-related molecules (E)-3-(4â ²- hydroxy-3â ²-adamantylbiphenyl-4-yl)acrylic acid (ST1926) and 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) in F9 teratocarcinoma: Role of retinoic acid receptor γ and retinoid-independent pathways | 1-gen-2006 | Parrella, Edoardo; Giannì, Maurizio; Fratelli, Maddalena; Barzago, Maria Monica; Raska Jr., Ivan; Diomede, Luisa; Kurosaki, Mami; Pisano, Claudio; Carminati, Paolo; Merlini, Lucio; Dallavalle, Sabrina; Tavecchio, Michele; Rochette-Egly, Cecile; Terao, Mineko; Garattini, Enrico | |
| Beneficial and Dimorphic Response to Combined HDAC Inhibitor Valproate and AMPK/SIRT1 Pathway Activator Resveratrol in the Treatment of ALS Mice | 1-gen-2022 | Bankole, Oluwamolakun; Scambi, Ilaria; Parrella, Edoardo; Muccilli, Matilde; Bonafede, Roberta; Turano, Ermanna; Pizzi, Marina; Mariotti, Raffaella | |
| c-Rel deficient mice, a mouse model of “spreading” PD-like pathology | 1-gen-2016 | Parrella, Edoardo; Bellucci, Arianna; Porrini, Vanessa; Lanzillotta, Annamaria; Benarese, Marina; Vegezzi, Gaia; Baiguera, Cristina; Antonini, Angelo; Franco Spano, Pier; Pizzi, Marina | |
| CHF5074 (CSP-1103) induces microglia alternative activation in plaque-free Tg2576 mice and primary glial cultures exposed to beta-amyloid | 1-gen-2015 | Porrini, Vanessa; Lanzillotta, Annamaria; Branca, Caterina; Benarese, Marina Augusta; Parrella, Edoardo; Lorenzini, L.; Calzà, L.; Flaibani, R.; Spano, Pier Franco; Imbimbo, B. P.; Pizzi, Marina | |
| Fasting-mimicking diet cycles reduce neuroinflammation to attenuate cognitive decline in Alzheimer's models | 1-gen-2022 | Rangan, Priya; Lobo, Fleur; Parrella, Edoardo; Rochette, Nicolas; Morselli, Marco; Stephen, Terri-Leigh; Cremonini, Anna Laura; Tagliafico, Luca; Persia, Angelica; Caffa, Irene; Monacelli, Fiammetta; Odetti, Patrizio; Bonfiglio, Tommaso; Nencioni, Alessio; Pigliautile, Martina; Boccardi, Virginia; Mecocci, Patrizia; Pike, Christian J; Cohen, Pinchas; Ladu, Mary Jo; Pellegrini, Matteo; Xia, Kyle; Tran, Katelynn; Ann, Brandon; Chowdhury, Dolly; Longo, Valter D | |
| From preclinical stroke models to humans: Polyphenols in the prevention and treatment of stroke | 1-gen-2021 | Parrella, Edoardo; Gussago, Cristina; Porrini, Vanessa; Benarese, Marina; Pizzi, Marina | |
| Glial response and neuronal modulation induced by epidural electrode implant in the pilocarpine mouse model of epilepsy | 1-gen-2024 | Spagnoli, Giulia; Parrella, Edoardo; Ghazanfar Tehrani, Sara; Mengoni, Francesca; Salari, Valentina; Nistreanu, Cristina; Scambi, Ilaria; Sbarbati, Andrea; Bertini, Giuseppe; Fabene, Paolo Francesco | |
| Inhibition of the peptidyl-prolyl-isomerase Pin1 enhances the responses of acute myeloid leukemia cells to retinoic acid via stabilization of RARα and PML-RARα | 1-gen-2009 | Gianni', Maurizio; Boldetti, Andrea; Guarnaccia, Valeria; Rambaldi, Alessandro; Parrella, Edoardo; Raska Jr., Ivan; Rochette-Egly, Cecile; Del Sal, Giannino; Rustighi, Alessandra; Terao, Mineko; Garattini, Enrico | |
| Insulin/IGF-I and related signaling pathways regulate aging in nondividing cells: From yeast to the mammalian brain | 1-gen-2010 | Parrella, Edoardo; Longo, Valter D. | |
| Mild inflammatory profile without gliosis in the c-rel deficient mouse modeling a late-onset parkinsonism | 1-gen-2017 | Porrini, Vanessa; Mota, Mariana; Parrella, Edoardo; Bellucci, Arianna; Benarese, Marina; Faggi, Lara; Tonin, Paolo; Spano, Pier F.; Pizzi, Marina | |
| Neuroprotective and Anti-Apoptotic Effects of CSP-1103 in Primary Cortical Neurons Exposed to Oxygen and Glucose Deprivation | 1-gen-2017 | Porrini, Vanessa; Sarnico, Ilenia Tiziana; Benarese, Marina Augusta; Branca, Caterina; COELHO DA MOTA, Mariana; Lanzillotta, Annamaria; Bellucci, Arianna; Parrella, Edoardo; Faggi, Lara; Spano, Pier Franco; Imbimbo, Bruno Pietro; Pizzi, Marina | |
| Neuroprotective epi-drugs quench the inflammatory response and microglial/macrophage activation in a mouse model of permanent brain ischemia | 1-gen-2020 | Mota, Mariana; Porrini, Vanessa; Parrella, Edoardo; Benarese, Marina; Bellucci, Arianna; Rhein, Sina; Schwaninger, Markus; Pizzi, Marina | |
| NF-κB in Innate Neuroprotection and Age-Related Neurodegenerative Diseases | 1-gen-2015 | Lanzillotta, Annamaria; Porrini, Vanessa; Bellucci, Arianna; Benarese, Marina Augusta; Branca, Caterina; Parrella, Edoardo; Spano, Pier Franco; Pizzi, Marina | |
| NF-κB unbalance and dysfunction in acute and age-related neurodegenerative disease | 1-gen-2014 | Lanzillotta, A; Porrini, V; Bellucci, A; Benarese, M; Branca, C; Parrella, E; Spano, Pf; Pizzi, M | |
| NF-κB/c-Rel deficiency causes Parkinson's disease-like prodromal symptoms and progressive pathology in mice | 1-gen-2019 | Parrella, Edoardo; Bellucci, Arianna; Porrini, Vanessa; Benarese, Marina; Lanzillotta, Annamaria; Faustini, Gaia; Longhena, Francesca; Abate, Giulia; Uberti, Daniela; Pizzi, Marina | |
| Nuclear Factor-κB Dysregulation and α-Synuclein Pathology: Critical Interplay in the Pathogenesis of Parkinson’s Disease | 1-gen-2020 | Bellucci, A.; Bubacco, L.; Longhena, F.; Parrella, Edoardo; Faustini, G.; Porrini, V.; Bono, F.; Missale, C.; Pizzi, M. | |
| P38MAPK-dependent phosphorylation and degradation of SRC-3/AIB1 and RARα-mediated transcription | 1-gen-2006 | Giannì, Maurizio; Parrella, Edoardo; Raska Jr., Ivan; Gaillard, Emilie; Nigro, Elisa Agnese; Gaudon, Claudine; Garattini, Enrico; Rochette-Egly, Cécile |