Within the field of aesthetic medicine, various methodologies have been employed to combat skin aging, particularly in the facial region. One such approach involves the utilization of hyaluronic acid to enhance water retention and support extracellular matrix integrity. This research aims to clinically and histologically assess the impact of combining low molecular weight hyaluronic acid fragments with amino acids (HAAM) on revitalizing facial skin through intradermal microinjections. A cohort of twenty female participants, with an average age of 45 falling within the range of 35 to 64, was included in this investigation. Among them, eight were in the postmenopausal stage, while twelve were in their childbearing years. Mesotherapy was employed to administer HAAM products to the patients for 4 section. The outcomes from the current investigation revealed that applying hyaluronic acid with fragments of 20 to 38 monomers, along with amino acids through the dermal injection technique, leads to an enhancement in the visual appearance of the treated patients’ facial features. The clinical evaluation highlighted the significant influence of subcutaneous HAAM infiltration on both the dermis, improve pH levels, sebum production, skin hydration and enhance the overall clinical presentation of the facial region.

A CLINICAL INVESTIGATION OF HYALURONIC ACID FORTIFIED WITH AMINO ACIDS FOR ADDRESSING FACIAL AGING

Marchetti, Marco;
2024-01-01

Abstract

Within the field of aesthetic medicine, various methodologies have been employed to combat skin aging, particularly in the facial region. One such approach involves the utilization of hyaluronic acid to enhance water retention and support extracellular matrix integrity. This research aims to clinically and histologically assess the impact of combining low molecular weight hyaluronic acid fragments with amino acids (HAAM) on revitalizing facial skin through intradermal microinjections. A cohort of twenty female participants, with an average age of 45 falling within the range of 35 to 64, was included in this investigation. Among them, eight were in the postmenopausal stage, while twelve were in their childbearing years. Mesotherapy was employed to administer HAAM products to the patients for 4 section. The outcomes from the current investigation revealed that applying hyaluronic acid with fragments of 20 to 38 monomers, along with amino acids through the dermal injection technique, leads to an enhancement in the visual appearance of the treated patients’ facial features. The clinical evaluation highlighted the significant influence of subcutaneous HAAM infiltration on both the dermis, improve pH levels, sebum production, skin hydration and enhance the overall clinical presentation of the facial region.
2024
aesthetic enhancement
cutaneous biostimulation
hyaluronic acid fragments
skin imperfections
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14245/11046
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 2
social impact