We describe the case of a man who presented with spasticity and aphasia related to a continuous electroen- 22cephalographic epileptic activity in the left frontal–temporal regions. Magnetic resonance imaging (MRI) 23documented in diffusion-weighted images (DWI) two areas of restricted diffusion in the left frontal and tem- 24poral cortex. After starting treatment with levetiracetam 3000 mg/day was evident a progressive recovery of 25the clinical picture combined to both the gradual disappearance of the electroencephalographic seizure activ- 26Q4 ity and the vanishing of areas of restricted diffusion in brain MRI. Based on the clinical, EEG and MRI data, we 27hypothesized that both aphasia and spasticity represented ictal signs. To our knowledge, this is the first case 28report of ictal spasticity
Spasticity as an ictal pattern due to the excitotoxic upper motor neuron damage
Romigi, Andrea
2012-01-01
Abstract
We describe the case of a man who presented with spasticity and aphasia related to a continuous electroen- 22cephalographic epileptic activity in the left frontal–temporal regions. Magnetic resonance imaging (MRI) 23documented in diffusion-weighted images (DWI) two areas of restricted diffusion in the left frontal and tem- 24poral cortex. After starting treatment with levetiracetam 3000 mg/day was evident a progressive recovery of 25the clinical picture combined to both the gradual disappearance of the electroencephalographic seizure activ- 26Q4 ity and the vanishing of areas of restricted diffusion in brain MRI. Based on the clinical, EEG and MRI data, we 27hypothesized that both aphasia and spasticity represented ictal signs. To our knowledge, this is the first case 28report of ictal spasticityI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
