Evaluation of BiesseBioscreen as a new methodology for bacteriuria screening

Urinary tract infection is a common disease diagnosed from symptoms and clinical signs, and bacterial count pervolume of urine. This study have evaluated the BiesseBioscreen analyzer as a new way to analyze urine samples enablingfast screening of urine, prior to reference standard methods currently utilized in microbiology analysis laboratory.We analyzed 962 urine samples from outpatients and inpatients of the Tor Vergata (TV) University Hospitalof the University of Rome “Tor Vergata”. All samples were processed both with the BiesseBioscreen and with thestandard methodology adopted by the clinical microbiology laboratory of TV Hospital and the results were compared.Of the samples analyzed 54.9% were concordant negative with the reference method and 21.6% concordantpositive, 23.3% resulted false positive and 0.2% false negative. The results obtained from BiesseBioscreen showeda sensitivity of 99.0%, indicating it as a system suitable to rule out urinary tract infection. BiesseBioscreen couldrepresent a valid method for screening negative samples to exclude from culture test with a potential reduction intime, workload and costs of the diagnosis.