Phosphodiesterase 2A, a cAMP-hydrolysing enzyme, is essential for mouse development, however the cause of Pde2A knockout embryonic lethality is unknown. To understand if Pde2A plays a role in cardiac development, hearts of Pde2A deficient embryos were analysed at different stage of development.
Critical role of phosphodiesterase 2A in mouse congenital heart defects
Campolo, Federica;
2018-01-01
Abstract
Phosphodiesterase 2A, a cAMP-hydrolysing enzyme, is essential for mouse development, however the cause of Pde2A knockout embryonic lethality is unknown. To understand if Pde2A plays a role in cardiac development, hearts of Pde2A deficient embryos were analysed at different stage of development.File in questo prodotto:
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