Inflammation represents a complex biological response of the body to dangerous stimuli such as pathogens and involves different types of cells including immune cells (e.g., astrocytes and microglia), blood vessels, and molecular mediators. The main function of inflammation is to eradicate the causes responsible for cell injury, remove dead cells and damaged tissues, and allow the beginning of tissue repair. Carnosine is a dipeptide composed by β-alanine and l-histidine possessing multiple functions that include anti-aggregant, antioxidant, and anti-inflammatory activities. Carnosine has also been shown to accelerate the wound-healing process. Since numerous diseases are characterized by systemic and/or central inflammation such as cardiovascular diseases, type 2 diabetes mellitus, and neurodegenerative disorders, this molecule could be of great interest.
Carnosine and Inflammation
Caruso, Giuseppe;Lazzarino, Giacomo;
2024-01-01
Abstract
Inflammation represents a complex biological response of the body to dangerous stimuli such as pathogens and involves different types of cells including immune cells (e.g., astrocytes and microglia), blood vessels, and molecular mediators. The main function of inflammation is to eradicate the causes responsible for cell injury, remove dead cells and damaged tissues, and allow the beginning of tissue repair. Carnosine is a dipeptide composed by β-alanine and l-histidine possessing multiple functions that include anti-aggregant, antioxidant, and anti-inflammatory activities. Carnosine has also been shown to accelerate the wound-healing process. Since numerous diseases are characterized by systemic and/or central inflammation such as cardiovascular diseases, type 2 diabetes mellitus, and neurodegenerative disorders, this molecule could be of great interest.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
