Cushing's disease, i.e. cortisol excess due to an ACTH-secreting pituitary adenoma, is a rare disorder with considerable morbidity and mortality but no satisfactory medical treatment as yet. Experimental data have recently shown that retinoic acid restrains ACTH secretion by tumoral corticotropes.

Potential role for retinoic acid in patients with Cushing's disease

Corsello, Salvatore Maria;
2012-01-01

Abstract

Cushing's disease, i.e. cortisol excess due to an ACTH-secreting pituitary adenoma, is a rare disorder with considerable morbidity and mortality but no satisfactory medical treatment as yet. Experimental data have recently shown that retinoic acid restrains ACTH secretion by tumoral corticotropes.
2012
ACTH-Secreting Pituitary Adenoma
Adenoma
Adolescent
Adrenocorticotropic Hormone
Adult
Antineoplastic Agents
Female
Humans
Hydrocortisone
Male
Middle Aged
Pituitary ACTH Hypersecretion
Prospective Studies
Treatment Outcome
Tretinoin
Young Adult
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14245/986
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