IRIS
D'Orazi, Gabriella
 Distribuzione geografica
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Continente #
AS - Asia 2.338
NA - Nord America 2.153
SA - Sud America 906
EU - Europa 389
AF - Africa 130
Continente sconosciuto - Info sul continente non disponibili 1
OC - Oceania 1
Totale 5.918
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Nazione #
US - Stati Uniti d'America 1.971
SG - Singapore 750
BR - Brasile 681
CN - Cina 502
BD - Bangladesh 264
HK - Hong Kong 220
IT - Italia 218
VN - Vietnam 176
IN - India 106
MX - Messico 82
AR - Argentina 76
CA - Canada 52
IQ - Iraq 50
CO - Colombia 39
ID - Indonesia 39
FR - Francia 34
ZA - Sudafrica 34
SA - Arabia Saudita 32
EC - Ecuador 31
GB - Regno Unito 31
PK - Pakistan 29
TR - Turchia 26
UZ - Uzbekistan 26
VE - Venezuela 22
RU - Federazione Russa 20
TN - Tunisia 20
UA - Ucraina 18
MA - Marocco 17
MY - Malesia 17
JM - Giamaica 15
KE - Kenya 14
PH - Filippine 14
PY - Paraguay 14
BO - Bolivia 13
CL - Cile 12
EG - Egitto 10
ET - Etiopia 10
AE - Emirati Arabi Uniti 9
DE - Germania 9
JO - Giordania 9
NP - Nepal 9
PE - Perù 9
NL - Olanda 8
UY - Uruguay 8
ES - Italia 7
PL - Polonia 7
PS - Palestinian Territory 6
PT - Portogallo 6
AZ - Azerbaigian 5
BH - Bahrain 5
CR - Costa Rica 5
DZ - Algeria 5
HN - Honduras 5
IL - Israele 5
KZ - Kazakistan 5
NI - Nicaragua 5
TH - Thailandia 5
AL - Albania 4
DO - Repubblica Dominicana 4
JP - Giappone 4
LB - Libano 4
OM - Oman 4
PA - Panama 4
DK - Danimarca 3
HU - Ungheria 3
IE - Irlanda 3
LY - Libia 3
MD - Moldavia 3
RS - Serbia 3
SN - Senegal 3
TT - Trinidad e Tobago 3
BF - Burkina Faso 2
BG - Bulgaria 2
CH - Svizzera 2
CY - Cipro 2
GE - Georgia 2
KR - Corea 2
LA - Repubblica Popolare Democratica del Laos 2
NG - Nigeria 2
RE - Reunion 2
SV - El Salvador 2
AD - Andorra 1
AO - Angola 1
AU - Australia 1
BB - Barbados 1
BE - Belgio 1
BN - Brunei Darussalam 1
BS - Bahamas 1
BY - Bielorussia 1
CI - Costa d'Avorio 1
CU - Cuba 1
GA - Gabon 1
GF - Guiana Francese 1
KG - Kirghizistan 1
KH - Cambogia 1
KW - Kuwait 1
KY - Cayman, isole 1
LU - Lussemburgo 1
ML - Mali 1
MO - Macao, regione amministrativa speciale della Cina 1
Totale 5.904
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Città #
San Jose 1.153
Singapore 418
Ashburn 325
Beijing 233
Hong Kong 217
Rome 87
Ho Chi Minh City 73
Santa Clara 55
Mexico City 52
São Paulo 52
Hanoi 37
Tashkent 23
Baghdad 20
New York 20
Rio de Janeiro 20
Curitiba 18
Belo Horizonte 17
Dhaka 17
Quito 15
Medellín 14
Riyadh 13
Campinas 12
Buffalo 11
Caracas 11
Nairobi 11
Naples 11
Addis Ababa 10
Bogotá 10
Johannesburg 10
Kingston 10
Milan 10
Brasília 9
Jeddah 9
Los Angeles 9
Tunis 9
Casablanca 8
Houston 8
Mumbai 8
Amman 7
Chicago 7
Goiânia 7
Lahore 7
Montevideo 7
New Delhi 7
Asunción 6
Erbil 6
Guarulhos 6
Haiphong 6
Kuala Lumpur 6
Lima 6
Ludhiana 6
Recife 6
Salvador 6
Atlanta 5
Biên Hòa 5
Bologna 5
Calgary 5
Dubai 5
Durban 5
Fortaleza 5
Frankfurt am Main 5
Istanbul 5
Managua 5
Manaus 5
Milwaukee 5
Osasco 5
Petaling Jaya 5
Philadelphia 5
Porto Alegre 5
Santiago 5
Sorocaba 5
The Bronx 5
Toronto 5
Baku 4
Brooklyn 4
Buenos Aires 4
Cairo 4
Cape Town 4
Caxias do Sul 4
Chennai 4
Dammam 4
Delhi 4
Diadema 4
Fort Worth 4
Jequié 4
Karachi 4
Karbala 4
Kathmandu 4
Kyiv 4
La Paz 4
Las Vegas 4
London 4
Maringá 4
Montreal 4
Newark 4
Phoenix 4
Piracicaba 4
Pretoria 4
Quimilí 4
Ribeirão das Neves 4
Totale 3.349
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Nome #
Mutant p53 and cellular stress pathways: A criminal alliance that promotes cancer progression 72
KSHV infection skews macrophage polarisation towards M2-like/TAM and activates Ire1 α-XBP1 axis up-regulating pro-tumorigenic cytokine release and PD-L1 expression 61
Zinc supplementation augments in vivo antitumor effect of chemotherapy by restoring p53 function 56
Follicle-stimulating hormone increases the expression of tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2 and induces TIMP-1 AP-1 site binding complex(es) in prepubertal rat Sertoli cells 56
Reduced chemotherapeutic sensitivity in high glucose condition: implication of antioxidant response 54
Hyperglycemia triggers HIPK2 protein degradation 49
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) 49
Zinc downregulates HIF-1α and inhibits its activity in tumor cells in vitro and in vivo 43
HIPK2-a therapeutical target to be (re)activated for tumor suppression: role in p53 activation and HIF-1α inhibition 41
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 41
HIPK2 as a Novel Regulator of Fibrosis 41
A ruthenium(II)-curcumin compound modulates NRF2 expression balancing the cancer cell death/survival outcome according to p53 status 41
Mutant p53 upregulates HDAC6 to resist ER stress and facilitates Ku70 deacetylation, which prevents its degradation and mitigates DNA damage in colon cancer cells 40
SAHA/5-AZA Enhances Acetylation and Degradation of mutp53, Upregulates p21 and Downregulates c-Myc and BRCA-1 in Pancreatic Cancer Cells 40
Oncogenic pathways activated by pro-inflammatory cytokines promote mutant p53 stability: clue for novel anticancer therapies 40
The 72-kDa and the 92-kDa gelatinases, but not their inhibitors TIMP-1 and TIMP-2, are expressed in early psoriatic lesions 39
Interplay between endoplasmic reticulum (ER) stress and autophagy induces mutant p53H273 degradation 39
Targeting hypoxia in tumor: a new promising therapeutic strategy 38
Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways 38
Targeting mutant p53 in cancer: the latest insights 38
Zn(II)-curc targets p53 in thyroid cancer cells 38
HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function 37
ATF6 supports lysosomal function in tumor cells to enable ER stress-activated macroautophagy and CMA: impact on mutant TP53 expression 36
HIPK2 modulates p53 activity towards pro-apoptotic transcription 36
Zinc supplementation is required for the cytotoxic and immunogenic effects of chemotherapy in chemoresistant p53-functionally deficient cells 36
Ultrastructurale evidence of the mechanism responsible for Interleukin-4 activated rejection of a spontaneous murine adenocarcinoma 36
HIPK2 in Angiogenesis: A Promising Biomarker in Cancer Progression and in Angiogenic Diseases 36
Quercetin Interrupts the Positive Feedback Loop Between STAT3 and IL-6, Promotes Autophagy, and Reduces ROS, Preventing EBV-Driven B Cell Immortalization 36
Targeting hypoxia in cancer cells by restoring homeodomain interacting protein-kinase 2 and p53 activity and suppressing HIF-1alpha 36
Oxidant species are involved in T/B-mediated ERK1/2 phosphorylation that activates p53-p21 axis to promote KSHV lytic cycle in PEL cells 35
Aspetti ultrastrutturali ed immunochimici della componente vasale del timo in condizioni normali e patologiche 35
Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies 35
Role of upr sensor activation in cell death–survival decision of colon cancer cells stressed by dpe treatment 35
NFE2L2 and STAT3 Converge on Common Targets to Promote Survival of Primary Lymphoma Cells 35
P62/SQSTM1/Keap1/NRF2 Axis Reduces Cancer Cells Death-Sensitivity in Response to Zn(II)-Curcumin Complex 34
N6-Methyldeoxyadenosine, a nucleoside commonly found in prokaryotes, induces C2C12 myogenic differentiation 34
The beneficial effect of Zinc(II) on low-dose chemotherapeutic sensitivity involves p53 activation in wild-type p53-carrying colorectal cancer cells 34
Hypoxia-inducible factor -1 (HIF-1) antagonizes p53-mediated apoptosis 34
Updates on HIPK2: a resourceful oncosuppressor for clearing cancer 34
Valemetostat–SAHA-Driven Acetylation of p53 via SET/TAF-Iβ Displacement and p300 Activation Modulates Cell Cycle Regulators in Pancreatic Cancer Cells 34
Inhibition of HIF-1alpha activity by homeodomain-interacting protein kinase-2 correlates with sensitization of chemoresistant cells to undergo apoptosis 33
Ewing's sarcoma lines synthesize laminin and fibronectin 33
Anticancer effect of AZD2461 PARP inhibitor against colon cancer cells carrying wt or dysfunctional p53 33
Recent Advances on Mutant p53: Unveiling Novel Oncogenic Roles, Degradation Pathways, and Therapeutic Interventions 32
NRF2 and Bip Interconnection Mediates Resistance to the Organometallic Ruthenium-Cymene Bisdemethoxycurcumin Complex Cytotoxicity in Colon Cancer Cells 32
A fluorescent curcumin-based Zn(II)-complex reactivates mutant (R175H and R273H) p53 in cancer cells 32
Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro 32
VPA and TSA Interrupt the Interplay between mutp53 and HSP70, Leading to CHK1 and RAD51 Down-Regulation and Sensitizing Pancreatic Cancer Cells to AZD2461 PARP Inhibitor 32
Use of zinc in combination with chemotherapy for treating cancer 32
Activation of p53-dependent apoptosis in HIPK2 depleted tumor cells: an approach of combination therapy with drug, zinc, and deacetylase inhibitors 32
Autophagy manipulation as a strategy for efficient anticancer therapies: Possible consequences 31
Immunohystochemical distribution of type IV gelatinase A and type V collagen in ductal invasive carcinoma 31
HIPK2 knock-down compromises tumor cell efficiency to repair damaged DNA 31
p53 can inhibit cell proliferation through caspase-mediated cleavage of ERK2/MAPK 31
Carvacrol reduces adipogenic differentiation by modulating autophagy and ChREBP expression 31
Chloroquine supplementation increases the cytotoxic effect of curcumin against Her2/neu overexpressing breast cancer cells in vitro and in vivo in nude mice while counteracts it in immune competent mice 31
NRF2 activation in BON‑1 neuroendocrine cancer cells reduces the cytotoxic effects of a novel Ruthenium(II)‑curcumin compound: A pilot study 31
Establishment and characterization of a human continuous cell line from a IVs neuroblastoma 31
HSP70 inhibition by 2-phenylethynesulfonamide induces lysosomal cathepsin D release and immunogenic cell death in primary effusion lymphoma 30
Clearing mutant p53 with natural compounds: implication for anticancer therapeutical approaches 30
Xenotransplantion in immunodepressed nude mice of human solid tumors and acute leukemias directly from patients or in vitro cell lines 30
Morphologic study of the vasal component of human thymus and thimoma 30
HSP110 Inhibition in Primary Effusion Lymphoma Cells: One Molecule, Many Pro-Survival Targets 30
Sintesi di laminina da parte delle cellule NK e dei linfociti T di ratto 30
HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage 30
Azurin modulates the association of Mdm2 with p53: SPR evidence from interaction of the full-length proteins 30
Zinc Supplementation Enhances the Pro-Death Function of UPR in Lymphoma Cells Exposed to Radiation 30
P53-Dependent PUMA to DRAM antagonistic interplay as a key molecular switch in cell-fate decision in normal/high glucose conditions 30
Expression and synthesis of fibronectin (FN) by rat NK cells: Possible involvement in the NK-target interaction 30
Blockade of HIPK2 apoptotic function is involved in chemoresistance to cisplatin in ovarian cancer cells 30
ATF6 prevents DNA damage and cell death in colon cancer cells undergoing ER stress 30
Cytotoxic Drugs Activate KSHV Lytic Cycle in Latently Infected PEL Cells by Inducing a Moderate ROS Increase Controlled by HSF1, NRF2 and p62/SQSTM1 30
Novel approaches to target the p53 and hypoxia pathways for cancer therapy 29
P53 activity in normal and tumor cells 29
The Impact of NRF2 Inhibition on Drug-Induced Colon Cancer Cell Death and p53 Activity: A Pilot Study 29
Nuclear factor erythroid 2 (NF-E2) p45-related factor 2 interferes with homeodomain-interacting protein kinase 2/p53 activity to impair solid tumors chemosensitivity 29
Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation 28
HIPK2 inhibits both MDM2 gene and protein by, respectively, p53-dependent and independent regulations 28
Combination therapy strategies in HIPK2 knockdown tumor cells require Sirt1 inhibitor to activate p53 apoptotic transcription 28
Pyrazolone-Based Zn(II) Complexes Display Antitumor Effects in Mutant p53-Carrying Cancer Cells 28
Zinc supplementation counteracts cobalt-induced inhibition of homeodomain-interacting protein kinase-2 (HIPK2) and restores tumor chemosensitivity and p53 apoptotic function 28
Mutant P53, stabilized by its interplay with HSP90, activates a positive feed-back loop between NRF2 and P62 that induces chemo-resistance to apigenin in pancreatic cancer cells 28
Post-Translational Modifications (PTMs) of mutp53 and Epigenetic Changes Induced by mutp53 28
HIPK2 contributes to PCAF-mediated acetylation of p53 after non-apoptotic DNA damage 28
STAT3 and mutp53 Engage a Positive Feedback Loop Involving HSP90 and the Mevalonate Pathway 28
The Impact of COVID-19 Infection in Cancer 2020-2021 28
Glucose restriction induces cell death in parental but not in homeodomain-interacting protein kinase 2-depleted RKO colon cancer cells: molecular mechanisms and implications for tumor therapy 28
NRF2 in Cancer: Cross-Talk with Oncogenic Pathways and Involvement in Gammaherpesvirus-Driven Carcinogenesis 28
Tumor cell response to cisplatin requires HIPK2 and p53 phosphorylation at ser46 27
Gentian violet induces wtp53 transactivation in cancer cells 27
High glucose dephosphorylates serine 46 and inhibits p53 apoptotic activity 27
ERK2/MAPK, a new target for p53 in the cell cycle arrest 27
PBA preferentially impairs cell survival of glioblastomas carrying mutp53 by reducing its expression level, stabilizing wtp53, downregulating the mevalonate kinase and dysregulating UPR 27
Abrogation of p53 activity by HIPK2 down-regulation 27
Targeting COX-2/PGE(2) pathway in HIPK2 knockdown cancer cells: impact on dendritic cell maturation 27
Expression and synthesis of fibronectin and laminin by an intestinal epithelial cell line 27
HHV-6A infection dysregulates autophagy/UPR interplay increasing beta amyloid production and tau phosphorylation in astrocytoma cells as well as in primary neurons, possible molecular mechanisms linking viral infection to Alzheimer's disease 27
Sep corticali e midollari nel ratto dopo trauma spinale 27
Aspetti ultastrutturali di lingua e paradenzio di ratti alimentati con dieta aproteica 27
c-Myc Sustains Pancreatic Cancer Cell Survival and mutp53 Stability through the Mevalonate Pathway 27
Totale 3.389
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Categoria #
all - tutte 26.065
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 26.065
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2024/20251.311 0 0 0 24 51 21 91 74 267 46 345 392
2025/20264.762 266 36 352 351 434 262 429 226 1.078 650 314 364
2026/202787 87 0 0 0 0 0 0 0 0 0 0 0
Totale 6.160