IRIS
D'Orazi, Gabriella
 Distribuzione geografica
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Continente #
AS - Asia 195
EU - Europa 89
NA - Nord America 41
Totale 325
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Nazione #
SG - Singapore 145
IT - Italia 81
HK - Hong Kong 48
MX - Messico 21
US - Stati Uniti d'America 20
NL - Olanda 3
DE - Germania 2
ID - Indonesia 2
UA - Ucraina 2
BE - Belgio 1
Totale 325
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Città #
Singapore 96
Rome 65
Hong Kong 46
Mexico City 21
Santa Clara 2
Antwerp 1
Ashburn 1
Totale 232
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Nome #
Oncogenic pathways activated by pro-inflammatory cytokines promote mutant p53 stability: clue for novel anticancer therapies 19
A ruthenium(II)-curcumin compound modulates NRF2 expression balancing the cancer cell death/survival outcome according to p53 status 10
HIPK2 in Angiogenesis: A Promising Biomarker in Cancer Progression and in Angiogenic Diseases 9
Cisti odontogene dei mascellari: aspetti ultrastrutturali dello stroma 9
KSHV infection skews macrophage polarisation towards M2-like/TAM and activates Ire1 α-XBP1 axis up-regulating pro-tumorigenic cytokine release and PD-L1 expression 8
HIPK2 as a Novel Regulator of Fibrosis 8
ATF6 prevents DNA damage and cell death in colon cancer cells undergoing ER stress 8
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 7
NRF2 in Cancer: Cross-Talk with Oncogenic Pathways and Involvement in Gammaherpesvirus-Driven Carcinogenesis 7
Etiologia delle lesioni papillari vescicali: nota preliminare 6
ATF6 supports lysosomal function in tumor cells to enable ER stress-activated macroautophagy and CMA: impact on mutant TP53 expression 5
Recent Advances on Mutant p53: Unveiling Novel Oncogenic Roles, Degradation Pathways, and Therapeutic Interventions 5
HSP110 Inhibition in Primary Effusion Lymphoma Cells: One Molecule, Many Pro-Survival Targets 5
Targeting COX-2/PGE(2) pathway in HIPK2 knockdown cancer cells: impact on dendritic cell maturation 5
Pyrazolone-Based Zn(II) Complexes Display Antitumor Effects in Mutant p53-Carrying Cancer Cells 5
Inhibition of HIF-1alpha activity by homeodomain-interacting protein kinase-2 correlates with sensitization of chemoresistant cells to undergo apoptosis 5
Anticancer effect of AZD2461 PARP inhibitor against colon cancer cells carrying wt or dysfunctional p53 5
The Sweet Side of HIPK2 5
Interplay between endoplasmic reticulum (ER) stress and autophagy induces mutant p53H273 degradation 5
Zinc downregulates HIF-1α and inhibits its activity in tumor cells in vitro and in vivo 4
P62/SQSTM1/Keap1/NRF2 Axis Reduces Cancer Cells Death-Sensitivity in Response to Zn(II)-Curcumin Complex 4
The Role of Autophagy in Brain Tumors 4
Targeting hypoxia in tumor: a new promising therapeutic strategy 4
Unfolded p53 in the pathogenesis of Alzheimer's disease: is HIPK2 the link? 4
PBA preferentially impairs cell survival of glioblastomas carrying mutp53 by reducing its expression level, stabilizing wtp53, downregulating the mevalonate kinase and dysregulating UPR 4
New Copper-Based Metallodrugs with Anti-Invasive Capacity 4
Abrogation of p53 activity by HIPK2 down-regulation 4
VPA and TSA Interrupt the Interplay between mutp53 and HSP70, Leading to CHK1 and RAD51 Down-Regulation and Sensitizing Pancreatic Cancer Cells to AZD2461 PARP Inhibitor 4
Aspetti differenziativi in una coltura di cellule dell'epitelio intestinale e sintesi di matrice extracellulare 4
Use of zinc in combination with chemotherapy for treating cancer 4
Zinco come adiuvante nelle chemioterapie per la riattivazione del pathway oncosoppressorio HIPK2/p53 4
Kaposi sarcoma associated herpesvirus (KSHV) induces AKT hyperphosphorylation, bortezomib-resistance and GLUT-1 plasma membrane exposure in THP-1 monocytic cell line 3
Zinc supplementation augments in vivo antitumor effect of chemotherapy by restoring p53 function 3
N6-Methyldeoxyadenosine, a nucleoside commonly found in prokaryotes, induces C2C12 myogenic differentiation 3
Clearing mutant p53 with natural compounds: implication for anticancer therapeutical approaches 3
STAT3 phosphorylation affects p53/p21 axis and KSHV lytic cycle activation 3
Considerazioni clinico-prognostiche sui tumori carcinoidi dell’ileo 3
ERK2/MAPK, a new target for p53 in the cell cycle arrest 3
HIF-1α antagonizes p53-mediated apoptosis by triggering HIPK2 degradation 3
Histone deacetylase inhibitors VPA and TSA induce apoptosis and autophagy in pancreatic cancer cells 3
NRF2 and Bip Interconnection Mediates Resistance to the Organometallic Ruthenium-Cymene Bisdemethoxycurcumin Complex Cytotoxicity in Colon Cancer Cells 3
Restoring drug-induced apoptosis in hypoxia-treated tumor cells by modulating HIPK2/p53 and HIF-1alpha pathways 3
Targeting mutant p53 in cancer: the latest insights 3
Mutant p53 and cellular stress pathways: A criminal alliance that promotes cancer progression 3
Nox1 is involved in p53 deacetylation and suppression of its transcriptional activity and apoptosis 3
Lovastatin reduces PEL cell survival by phosphorylating ERK1/2 that blocks the autophagic flux and engages a cross-talk with p53 to activate p21 3
P53 activity in normal and tumor cells 3
SAHA/5-AZA Enhances Acetylation and Degradation of mutp53, Upregulates p21 and Downregulates c-Myc and BRCA-1 in Pancreatic Cancer Cells 3
HHV-6A infection dysregulates autophagy/UPR interplay increasing beta amyloid production and tau phosphorylation in astrocytoma cells as well as in primary neurons, possible molecular mechanisms linking viral infection to Alzheimer's disease 3
Activation of p53/p21waf1 pathway is associated with senescence during v-Ha-ras transformation of immortal C2C12 myoblasts 3
Zinc Supplementation Enhances the Pro-Death Function of UPR in Lymphoma Cells Exposed to Radiation 3
Modulation of laminin synthesis in human neuroblastoma cells during retinoic acid induced differentiation 3
New kinases in the p53 pathway 3
Aspetti ultastrutturali di lingua e paradenzio di ratti alimentati con dieta aproteica 3
Restoring wtp53 activity in HIPK2 depleted MCF7 cells by modulating metallothionein and zinc 3
PGE2 Released by Pancreatic Cancer Cells Undergoing ER Stress Transfers the Stress to DCs Impairing Their Immune Function 3
Ewing's sarcoma lines synthesize laminin and fibronectin 3
Interconnected Adaptive Responses: A Way Out for Cancer Cells to Avoid Cellular Demise 3
c-Myc Sustains Pancreatic Cancer Cell Survival and mutp53 Stability through the Mevalonate Pathway 3
HIPK2 in Colon Cancer: A Potential Biomarker for Tumor Progression and Response to Therapies 3
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) 3
Comparison between p53 knock-down and p53 functional inactivation in affecting apoptotic cell response to drug treatment 3
Post-Translational Modifications (PTMs) of mutp53 and Epigenetic Changes Induced by mutp53 3
NFE2L2 and STAT3 Converge on Common Targets to Promote Survival of Primary Lymphoma Cells 3
Cytotoxic Drugs Activate KSHV Lytic Cycle in Latently Infected PEL Cells by Inducing a Moderate ROS Increase Controlled by HSF1, NRF2 and p62/SQSTM1 3
Transcriptional regulation of hypoxia-inducible factor 1 alpha by HIPK2 suggests a novel mechanism to restrain tumor growth 3
Cancer Chemotherapy: Combination with Inhibitors (Volume I) 3
HSP70 inhibition by 2-phenylethynesulfonamide induces lysosomal cathepsin D release and immunogenic cell death in primary effusion lymphoma 2
Oxidant species are involved in T/B-mediated ERK1/2 phosphorylation that activates p53-p21 axis to promote KSHV lytic cycle in PEL cells 2
Il trasferimento genico di p53 induce iper-sensibilita‚ alle basse dosi di raggi X in cellule di glioblastoma: una nuova strategia per convertire il fenotipo radio-resistente in radio-sensibile 2
Ultrastructure of human breast carcinoma from a pleural effusion 2
Autophagy manipulation as a strategy for efficient anticancer therapies: Possible consequences 2
High glucose dephosphorylates serine 46 and inhibits p53 apoptotic activity 2
Wt-p53 has suppressor activity only in fully transformed cells 2
HIPK2 modulates p53 activity towards pro-apoptotic transcription 2
MDM2 transcriptional and posttranscriptional regulation by the HIPK2/p53 complex: a novel pathway for regulating p53 apoptotic function 2
Metformin triggers apoptosis in PEL cells and alters bortezomib-induced Unfolded Protein Response increasing its cytotoxicity and inhibiting KSHV lytic cycle activation 2
Immunohystochemical distribution of type IV gelatinase A and type V collagen in ductal invasive carcinoma 2
Laminin expression by rat lymphoid cells 2
JNK and macroautophagy activation by Bortezomib has a pro-survival effect in Primary Effusion Lymphoma cells 2
TP53 enhances the radiation-induced hypersensitivity in human glioblastoma cell lines with different endogenous p53 status 2
Exogenous and endogenous wt-p53 proteins are transcriptionally active in v-Ha-ras transformed C2C12 cells, but not in their non-transformed counterparts 2
HIPK2-a therapeutical target to be (re)activated for tumor suppression: role in p53 activation and HIF-1α inhibition 2
Zinc supplementation is required for the cytotoxic and immunogenic effects of chemotherapy in chemoresistant p53-functionally deficient cells 2
Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation 2
Wt-p53 interferes with the v-Ha-ras pathway by inactivating ERK2/MAPK 2
Counteracting MDM2-induced HIPK2 downregulation restores HIPK2/p53 apoptotic signaling in cancer cells 2
Follicle-stimulating hormone increases the expression of tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2 and induces TIMP-1 AP-1 site binding complex(es) in prepubertal rat Sertoli cells 2
HIPK2 role in the tumor-host interaction: Impact on fibroblasts transdifferentiation CAF-like 2
Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways 2
Ultrastructurale evidence of the mechanism responsible for Interleukin-4 activated rejection of a spontaneous murine adenocarcinoma 2
NRF2 and STAT3: friends or foes in carcinogenesis? 2
HIPK2 inhibits both MDM2 gene and protein by, respectively, p53-dependent and independent regulations 2
Regulation of vascular endothelial growth factor expression by homeodomain-interacting protein kinase-2 2
Reversible dysfunction of wild-type p53 following HIPK2 knock-down 2
Overexpression of HIPK2 circumvents the blockade of apoptosis in chemoresistant ovarian cancer cells 2
HIPK2 regulates beta-catenin level and transcriptional potential 2
Morphologic study of the vasal component of human thymus and thimoma 2
Immunohistochemical and ultrastructural studies on the thymus in normal and acute EAE rats 2
Novel approaches to target the p53 and hypoxia pathways for cancer therapy 2
Totale 358
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Categoria #
all - tutte 2.493
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 2.493
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2024/2025562 0 0 0 24 51 21 91 74 267 34 0 0
Totale 562